Liver-Directed AAV8 Booster Vaccine Expressing <i>Plasmodium falciparum</i> Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model.-论文-万方医学网

作者： Mohammad,Shahnaij ^[1] ; Mitsuhiro,Iyori ^[1] ; Hiroaki,Mizukami ^[2] ; Mayu,Kajino ^[1] ; Iroha,Yamagoshi ^[1] ; Intan,Syafira ^[1] ; Yenni,Yusuf ^[3] ; Ken,Fujiwara ^[4] ; Daisuke S,Yamamoto ^[5] ; Hirotomo,Kato ^[5] ; Nobuhiko,Ohno ^[4] ; Shigeto,Yoshida ^[1]

作者单位： Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kanazawa University, Kanazawa, Japan. ^[1] Division of Gene Therapy, Jichi Medical University, Shimotsuke, Japan. ^[2] Department of Parasitology, Faculty of Medicine, University of Hasanuddin, Makassar, Indonesia. ^[3] Division of Histology and Cell Biology, School of Medicine, Jichi Medical University, Shimotsuke, Japan. ^[4] Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Shimotsuke, Japan. ^[5]

主题词动物(Animals);抗体, 原虫(Antibodies, Protozoan);抗原, 原虫(Antigens, Protozoan);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系(Cell Line);依赖病毒(Dependovirus);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);HEK293细胞(HEK293 Cells);人类(Humans);免疫接种, 加强(Immunization, Secondary);免疫记忆(Immunologic Memory);肝(Liver);疟疾疫苗(Malaria Vaccines);疟疾, 恶性(Malaria, Falciparum);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);恶性疟原虫(Plasmodium falciparum);原虫蛋白质类(Protozoan Proteins);疫苗, DNA(Vaccines, DNA)

DOI 10.3389/fimmu.2021.612910

PMID 34248928

发布时间 2021-09-15

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Liver-Directed AAV8 Booster Vaccine Expressing <i>Plasmodium falciparum</i> Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model.

Frontiers in immunology

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Frontiers in immunology

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Liver-Directed AAV8 Booster Vaccine Expressing <i>Plasmodium falciparum</i> Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model.

Frontiers in immunology

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Frontiers in immunology

相关期刊

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