Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
第一作者:
Giuseppe,Campiani
第一单位:
Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.
作者:
主题词
剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);人类(Humans);特发性肺纤维化(Idiopathic Pulmonary Fibrosis);模型, 分子(Models, Molecular);分子结构(Molecular Structure);构效关系(Structure-Activity Relationship)
DOI
10.1021/acs.jmedchem.1c00184
PMID
34251197
发布时间
2024-04-02
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Journal of medicinal chemistry
9960-9988页
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