Extracellular vesicles derived from lung cancer cells exposed to intermittent hypoxia upregulate programmed death ligand 1 expression in macrophages.

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作者： Yuanling,Liu ^[1] ; Minzhen,Lu ^[2] ; Jianan,Chen ^[3] ; Siqi,Li ^[1] ; Yiyu,Deng ^[2] ; Shifang,Yang ^[3] ; Qiong,Ou ^[2] ; Jing,Li ^[3] ; Ping,Gao ^[1] ; Zeru,Luo ^[2] ; Ping,Yuan ^[3] ; Jianlong,Tan ^[4] ; Xinglin,Gao ^[2]

作者单位： The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China. ^[1] Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Zhongshan 2nd road No. 106, Guangzhou, 510080, China. ^[2] Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China. ^[3] Department of Critical Care and Emergency, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ^[4] The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China. xinglingao@hotmail.com. ^[5] Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Zhongshan 2nd road No. 106, Guangzhou, 510080, China. xinglingao@hotmail.com. ^[6] Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China. xinglingao@hotmail.com. ^[7]

关键词 Extracellular vesicle Macrophage Non-small-cell lung cancer Obstructive sleep apnea Programmed cell death-1 ligand

主题词癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);肺肿瘤(Lung Neoplasms);巨噬细胞(Macrophages);睡眠呼吸暂停,阻塞性(Sleep Apnea, Obstructive)

DOI 10.1007/s11325-021-02369-1

PMID 34254261

发布时间 2022-07-16

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