首页> Journal of experimental & clinical cancer research : CR> CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity.

CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity.

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第一作者： Valeria,Catena

第一单位： SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. valeria.catena@ifo.gov.it.

作者： Valeria,Catena ^[1] ; Tiziana,Bruno ^[2] ; Simona,Iezzi ^[2] ; Silvia,Matteoni ^[3] ; Annalisa,Salis ^[4] ; Cristina,Sorino ^[2] ; Gianluca,Damonte ^[4] ; Maurizio,Fanciulli ^[5]

作者单位： SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. valeria.catena@ifo.gov.it. ^[1] SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. ^[2] Unit of Cellular Networks and Molecular Therapeutic Targets, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. ^[3] Department of Experimental Medicine (DIMES), Biochemistry Section, University of Genoa, Viale Benedetto XV 1, 16132, Genoa, Italy. ^[4] SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. maurizio.fanciulli@ifo.gov.it. ^[5]

关键词 CK2 Cancer cells Cell proliferation Che-1 Histone acetylation Phosphorylation SV40 LT

医学主题词凋亡调节蛋白质类(Apoptosis Regulatory Proteins);酪蛋白激酶Ⅱ(Casein Kinase II);细胞增殖(Cell Proliferation);人类(Humans);磷酰化(Phosphorylation);阻遏蛋白质类(Repressor Proteins);转染(Transfection)

DOI 10.1186/s13046-021-02038-x

PMID 34266450

发布时间 2021-12-23

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