换一批
换一批A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
作者：
Maria,Pino [1]
;
Talha,Abid [1]
;
Susan,Pereira Ribeiro [2]
;
Venkata Viswanadh,Edara [3]
;
Katharine,Floyd [3]
;
Justin C,Smith [4]
;
Muhammad Bilal,Latif [2]
;
Gabriela,Pacheco-Sanchez [2]
;
Debashis,Dutta [1]
;
Shelly,Wang [1]
;
Sanjeev,Gumber [5]
;
Shannon,Kirejczyk [5]
;
Joyce,Cohen [6]
;
Rachelle L,Stammen [6]
;
Sherrie M,Jean [6]
;
Jennifer S,Wood [6]
;
Fawn,Connor-Stroud [6]
;
Jeroen,Pollet [7]
;
Wen-Hsiang,Chen [7]
;
Junfei,Wei [7]
;
Bin,Zhan [7]
;
Jungsoon,Lee [7]
;
Zhuyun,Liu [7]
;
Ulrich,Strych [7]
;
Neeta,Shenvi [8]
;
Kirk,Easley [8]
;
Daniela,Weiskopf [9]
;
Alessandro,Sette [10]
;
Justin,Pollara [11]
;
Dieter,Mielke [11]
;
Hongmei,Gao [11]
;
Nathan,Eisel [11]
;
Celia C,LaBranche [11]
;
Xiaoying,Shen [11]
;
Guido,Ferrari [11]
;
Georgia D,Tomaras [11]
;
David C,Montefiori [12]
;
Rafick P,Sekaly [13]
;
Thomas H,Vanderford [1]
;
Mark A,Tomai [14]
;
Christopher B,Fox [15]
;
Mehul S,Suthar [3]
;
Pamela A,Kozlowski [4]
;
Peter J,Hotez [7]
;
Mirko,Paiardini [16]
;
Maria Elena,Bottazzi [17]
;
Sudhir Pai,Kasturi [16]
作者单位：
Division of Microbiology and Immunology, Yerkes National Primate Research Center at Emory University, 954 Gatewood Rd, Atlanta, GA, U.S.A.
[1]
Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, U.S.A.
[2]
Division of Microbiology and Immunology, Yerkes National Primate Research Center at Emory University, 954 Gatewood Rd, Atlanta, GA, U.S.A.;Emory Vaccine Center at Emory University, 954, Gatewood Rd, Atlanta, GA, U.S.A.;Centers for Childhood Infections and Vaccines; Children's Healthcare of Atlanta and Emory University, Department of Pediatrics, Atlanta, GA, U.S.A.
[3]
Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, U.S.A.
[4]
Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, U.S.A.;Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
[5]
Division of Animal Resources, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
[6]
Texas Children's Center for Vaccine Development, Houston, TX, U.S.A.;Department of Pediatrics, Molecular Virology & Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, U.S.A.
[7]
Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, U.S.A.
[8]
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
[9]
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.;Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
[10]
Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
[11]
Department of Pediatrics, Molecular Virology & Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, U.S.A.;Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
[12]
Division of Microbiology and Immunology, Yerkes National Primate Research Center at Emory University, 954 Gatewood Rd, Atlanta, GA, U.S.A.;Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, U.S.A.
[13]
3M Corporate Research Materials Laboratory, St. Paul, MN, USA.
[14]
The Infectious Disease Research Institute, Seattle, WA, USA.
[15]
Division of Microbiology and Immunology, Yerkes National Primate Research Center at Emory University, 954 Gatewood Rd, Atlanta, GA, U.S.A. skastur@emory.edu bottazzi@bcm.edu mirko.paiardini@emory.edu.;Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, U.S.A.
[16]
Texas Children's Center for Vaccine Development, Houston, TX, U.S.A. skastur@emory.edu bottazzi@bcm.edu mirko.paiardini@emory.edu.;Department of Pediatrics, Molecular Virology & Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, U.S.A.
[17]
主题词
佐剂, 免疫(Adjuvants, Immunologic);投药, 吸入(Administration, Inhalation);投药, 鼻内(Administration, Intranasal);明矾化合物(Alum Compounds);动物(Animals);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系(Cell Line);细胞因子类(Cytokines);人类(Humans);免疫球蛋白G(Immunoglobulin G);肺(Lung);猕猴(Macaca mulatta);男(雄)性(Male);蛋白质结合(Protein Binding);酵母菌目(Saccharomycetales);病毒载量(Viral Load)
DOI
10.1126/sciimmunol.abh3634
PMID
34266981
发布时间
2024-09-29
- 浏览2
Science immunology
Science immunology
2021年6卷61期
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