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Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.

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第一作者： Emily C,Cherney

第一单位： Bristol Myers Squibb Research and Development, 3551 Lawrenceville, Princeton Road, Lawrence Township, New Jersey 08648, United States.

作者： Emily C,Cherney ^[1] ; Liping,Zhang ^[1] ; Weiwei,Guo ^[1] ; Audris,Huang ^[1] ; David,Williams ^[1] ; Steven,Seitz ^[1] ; Weifang,Shan ^[1] ; Xiao,Zhu ^[1] ; Johnni,Gullo-Brown ^[1] ; Derrick,Maley ^[1] ; Tai-An,Lin ^[1] ; John T,Hunt ^[1] ; Christine,Huang ^[1] ; Zheng,Yang ^[1] ; Celia J,D'Arienzo ^[1] ; Lorell N,Discenza ^[1] ; Asoka,Ranasinghe ^[1] ; Mary F,Grubb ^[1] ; Sarah C,Traeger ^[1] ; Xin,Li ^[1] ; Kathy A,Johnston ^[1] ; Lisa,Kopcho ^[1] ; Mark,Fereshteh ^[1] ; Kimberly A,Foster ^[1] ; Kevin,Stefanski ^[1] ; Diane,Delpy ^[1] ; Gopal,Dhar ^[2] ; Aravind,Anandam ^[2] ; Sandeep,Mahankali ^[2] ; Shweta,Padmanabhan ^[2] ; Prabhakar,Rajanna ^[2] ; Venkata,Murali ^[2] ; T Thanga,Mariappan ^[2] ; Shabeerali,Pattasseri ^[2] ; Roshan Y,Nimje ^[2] ; Zhenqiu,Hong ^[1] ; James,Kempson ^[1] ; Richard,Rampulla ^[1] ; Arvind,Mathur ^[1] ; Anuradha,Gupta ^[2] ; Robert,Borzilleri ^[1] ; Gregory,Vite ^[1] ; Aaron,Balog ^[1]

作者单位： Bristol Myers Squibb Research and Development, 3551 Lawrenceville, Princeton Road, Lawrence Township, New Jersey 08648, United States. ^[1] Department of Discovery Synthesis, Biocon Bristol Myers Squibb R&D Centre, Syngene International Ltd., Biocon Park, Plot No. 2 & 3, Bommasandra-Jigani Road, Bangalore 560099, India. ^[2]

DOI 10.1021/acsmedchemlett.1c00236

PMID 34267885

发布时间 2022-07-16

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