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Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.

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第一作者： Shataakshi Dube,O'Neil

第一单位： Department of Neurobiology, Duke University Medical Center, Durham, United States.

作者： Shataakshi Dube,O'Neil ^[1] ; Bence,Rácz ^[2] ; Walter Evan,Brown ^[3] ; Yudong,Gao ^[3] ; Erik J,Soderblom ^[4] ; Ryohei,Yasuda ^[5] ; Scott H,Soderling ^[6]

作者单位： Department of Neurobiology, Duke University Medical Center, Durham, United States. ^[1] Department of Anatomy and Histology, University of Veterinary Medicine, Budapest, Hungary. ^[2] Department of Cell Biology, Duke University Medical Center, Durham, United States. ^[3] Department of Cell Biology, Duke University Medical Center, Durham, United States.;Proteomics and Metabolomics Shared Resource and Center for Genomic and Computational Biology, Duke University Medical Center, Durham, United States. ^[4] Max Planck Florida Institute for Neuroscience, Jupiter, United States. ^[5] Department of Neurobiology, Duke University Medical Center, Durham, United States.;Department of Cell Biology, Duke University Medical Center, Durham, United States. ^[6]

关键词 2pFLIM Rac1 cell biology cytoskeleton mouse neuroscience presynapse proteomics short-term plasticity

医学主题词肌动蛋白类(Actins);动作电位(Action Potentials);动物(Animals);钙(Calcium);细胞骨架(Cytoskeleton);海马(Hippocampus);小鼠(Mice);神经元可塑性(Neuronal Plasticity);神经肽类(Neuropeptides);蛋白质组学(Proteomics);突触(Synapses);突触小泡(Synaptic Vesicles);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein);ρGTP结合蛋白质类(rho GTP-Binding Proteins)

DOI 10.7554/eLife.63756

PMID 34269176

发布时间 2021-11-01

基金项目

R01 MH080047/MH/NIMH NIH HHS/United States R01 MH126954/MH/NIMH NIH HHS/United States R01 NS102456/NS/NINDS NIH HHS/United States R35 NS116804/NS/NINDS NIH HHS/United States R01 MH111684/MH/NIMH NIH HHS/United States

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