A Randomized, Multicenter, Open-Label, Blinded End Point, Phase 2, Feasibility, Efficacy, and Safety Trial of Preoperative Microvascular Protection in Patients Undergoing Major Abdominal Surgery.-论文-万方医学网

作者： Fumitaka,Yanase ^[1] ; Shervin H,Tosif ^[2] ; Leonid,Churilov ^[3] ; Ken,Yee ^[4] ; Rinaldo,Bellomo ^[5] ; Kerry,Gunn ^[1] ; Chang,Kim ^[2] ; Camilla,Krizhanovskii ^[5] ; Robert G,Hahn ^[5] ; Bernhard,Riedel ^[6] ; Laurence,Weinberg ^[7]

作者单位： From the Department of Intensive Care, Austin Hospital, Melbourne, Australia. ^[1] Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. ^[2] Department of Anaesthesia, Austin Hospital, Melbourne, Australia. ^[3] Department of Medicine (Austin Health) & Melbourne Brain Centre at Royal Melbourne Hospital, Melbourne Medical School Faculty of Medicine, The University of Melbourne, Melbourne, Australia. ^[4] Department of Anaesthesia, Auckland City Hospital, Auckland, New Zealand. ^[5] Department of Research, Södertälje Hospital, Södertälje, Sweden. ^[6] Department of Molecular Medicine and Surgery, Karolinska Institute, Solna, Sweden. ^[7] Karolinska Institute at Danderyd's Hospital (KIDS), Stockholm, Sweden. ^[8] Department of Anaesthesia, Perioperative and Pain Medicine, Peter MacCallum Cancer Centre; and the Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia. ^[9] Department of Critical Care, University of Melbourne, Melbourne, Australia. ^[10]

主题词腹部(Abdomen);老年人(Aged);白蛋白类(Albumins);C反应蛋白质(C-Reactive Protein);地塞米松(Dexamethasone);消化系统外科手术(Digestive System Surgical Procedures);内皮, 血管(Endothelium, Vascular);可行性研究(Feasibility Studies);女(雌)性(Female);糖皮质激素类(Glucocorticoids);多糖包被(Glycocalyx);硫酸乙酰肝素(Heparitin Sulfate);人类(Humans);输注, 静脉内(Infusions, Intravenous);男(雄)性(Male);微血管(Microvessels);中年人(Middle Aged);新西兰(New Zealand);手术后并发症(Postoperative Complications);手术前护理(Preoperative Care);多配体蛋白聚糖1(Syndecan-1);时间因素(Time Factors);治疗结果(Treatment Outcome);维多利亚(Victoria)

DOI 10.1213/ANE.0000000000005667

PMID 34269720

发布时间 2023-07-21

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A Randomized, Multicenter, Open-Label, Blinded End Point, Phase 2, Feasibility, Efficacy, and Safety Trial of Preoperative Microvascular Protection in Patients Undergoing Major Abdominal Surgery.

Anesthesia and analgesia

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A Randomized, Multicenter, Open-Label, Blinded End Point, Phase 2, Feasibility, Efficacy, and Safety Trial of Preoperative Microvascular Protection in Patients Undergoing Major Abdominal Surgery.

Anesthesia and analgesia

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Anesthesia and analgesia

相关期刊

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