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Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma.

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作者单位: Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Singapore 138648, Singapore. [1] Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Singapore 138648, Singapore; Emerging Infectious Disease Program, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore; Inserm U1015, Institut Gustave Roussy, 114 rue Edouard Vaillant, 94800 Villejuif, France. [2] Genome Institute of Singapore, A(∗)STAR, 60 Biopolis Street, Singapore 138672, Singapore. [3] Department of Immunology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. [4] Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Singapore 138648, Singapore; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109, USA. [5] Division of Medical Oncology, National Cancer Center Singapore, 11 Hospital Drive, Singapore 169610, Singapore. [6] Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Singapore 138648, Singapore; Division of Pathology, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore. [7] Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore. [8] Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore; Division of Surgery and Surgical Oncology, National Cancer Center Singapore, 11 Hospital Drive, Singapore 169610, Singapore. [9] Department of Reproductive Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore; Obstetrics and Gynaecology Academic Clinical Program, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore. [10] Division of Medical Oncology, National Cancer Center Singapore, 11 Hospital Drive, Singapore 169610, Singapore; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore. [11] Division of Gastroenterology and Hepatology, National University Health System, 1E Kent Ridge Road, Singapore 119228, Singapore. [12] Genome Institute of Singapore, A(∗)STAR, 60 Biopolis Street, Singapore 138672, Singapore; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China. [13] Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Singapore 138648, Singapore; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109, USA. Electronic address: enewell@fredhutch.org. [14]
DOI 10.1016/j.immuni.2021.06.013
PMID 34270940
发布时间 2021-09-23
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Immunity

Immunity

2021年54卷8期

1825-1840.e7页

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