Inhibitory activities of 20(R, S)-protopanaxatriol against epidermal growth factor receptor tyrosine kinase.

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作者： Jingqi,Zhao ^[1] ; Tiehua,Zhang ^[1] ; Yuan,Liang ^[1] ; Haoyang,Zou ^[1] ; Jie,Zhang ^[2]

作者单位： College of Food Science and Engineering, Jilin University, Changchun, 130062, China. ^[1] College of Food Science and Engineering, Jilin University, Changchun, 130062, China. Electronic address: zhangjie83@jlu.edu.cn. ^[2]

关键词 20(R, S)-protopanaxatriol [20(R, S)-PPT]Epidermal growth factor receptor (EGFR)Mitogen-activated protein kinase (MAPK)Tyrosine kinase inhibitors (TKIs)

主题词抗肿瘤药(Antineoplastic Agents);细胞增殖(Cell Proliferation);Hep G2细胞(Hep G2 Cells);人类(Humans);分子动力学模拟(Molecular Dynamics Simulation);蛋白激酶抑制剂(Protein Kinase Inhibitors);皂角苷配基(Sapogenins);立体异构现象(Stereoisomerism)

DOI 10.1016/j.fct.2021.112411

PMID 34271119

发布时间 2021-12-14

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Food and chemical toxicology

2021年155卷

112411页

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Inhibitory activities of 20(R, S)-protopanaxatriol against epidermal growth factor receptor tyrosine kinase.

Food and chemical toxicology

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Food and chemical toxicology

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Inhibitory activities of 20(R, S)-protopanaxatriol against epidermal growth factor receptor tyrosine kinase.

Food and chemical toxicology

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Food and chemical toxicology

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