首页> Cardiovascular research> Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells.

Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells.

导出 OA

翻译打印收藏纠错

第一作者： Ploingarm,Petsophonsakul

第一单位： Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.

作者： Ploingarm,Petsophonsakul ^[1] ; Mathias,Burgmaier ^[2] ; Brecht,Willems ^[1] ; Sylvia,Heeneman ^[3] ; Nadina,Stadler ^[3] ; Felix,Gremse ^[4] ; Sebastian,Reith ^[5] ; Kathrin,Burgmaier ^[6] ; Florian,Kahles ^[7] ; Nikolaus,Marx ^[7] ; Ehsan,Natour ^[8] ; Elham,Bidar ^[8] ; Michael,Jacobs ^[9] ; Barend,Mees ^[9] ; Chris,Reutelingsperger ^[1] ; Malgorzata,Furmanik ^[1] ; Leon,Schurgers ^[10]

作者单位： Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. ^[1] Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.;Department of Cardiology, Medical Clinic I, University Hospital of the RWTH Aachen, Aachen, Germany. ^[2] Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. ^[3] Experimental Molecular Imaging, University Hospital of the RWTH Aachen, Aachen, Germany. ^[4] Department of Cardiology, St. Franziskus Hospital Münster, Münster, Germany. ^[5] Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany. ^[6] Department of Cardiology, Medical Clinic I, University Hospital of the RWTH Aachen, Aachen, Germany. ^[7] Department of Cardiovascular Surgery, Maastricht University Medical Center (MUMC), Maastricht, The Netherlands.;Department of Vascular Surgery, European Vascular Center Aachen-Maastricht, Maastricht, The Netherlands. ^[8] Department of Vascular Surgery, European Vascular Center Aachen-Maastricht, Maastricht, The Netherlands.;Department of Vascular Surgery, Maastricht University Medical Center (MUMC), Maastricht, The Netherlands. ^[9] Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.;Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany. ^[10]

关键词 Nicotine Vascular calcification Vascular smooth muscle cell phenotypic switching Nox5 Vitamin K2