Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2-Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology.

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第一作者： C Allison,Stewart

第一单位： Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

作者： C Allison,Stewart ^[1] ; Carl M,Gay ^[1] ; Kavya,Ramkumar ^[1] ; Kasey R,Cargill ^[1] ; Robert J,Cardnell ^[1] ; Monique B,Nilsson ^[1] ; Simon,Heeke ^[1] ; Elizabeth M,Park ^[1] ; Samrat T,Kundu ^[1] ; Lixia,Diao ^[2] ; Qi,Wang ^[2] ; Li,Shen ^[2] ; Yuanxin,Xi ^[2] ; Bingnan,Zhang ^[1] ; Carminia Maria,Della Corte ^[3] ; Youhong,Fan ^[1] ; Kiran,Kundu ^[1] ; Boning,Gao ^[4] ; Kimberley,Avila ^[4] ; Curtis R,Pickering ^[5] ; Faye M,Johnson ^[1] ; Jianjun,Zhang ^[1] ; Humam,Kadara ^[6] ; John D,Minna ^[4] ; Don L,Gibbons ^[1] ; Jing,Wang ^[2] ; John V,Heymach ^[1] ; Lauren Averett,Byers ^[7]

作者单位： Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[1] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[2] Oncology Division, Department of Precision Medicine, University of Campania "Luigi Vanvitelli," Naples, Italy. ^[3] Department of Internal Medicine and Pharmacology, Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, Texas. ^[4] Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[5] Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[6] Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: lbyers@mdanderson.org. ^[7]

关键词 ACE2 AXL EMT NSCLC SARS-CoV-2 ZEB1

主题词支气管(Bronchi);人类(Humans);肺(Lung);肺肿瘤(Lung Neoplasms);肽基二肽酶A(Peptidyl-Dipeptidase A)

DOI 10.1016/j.jtho.2021.07.002

PMID 34274504

发布时间 2024-09-23

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