首页> Blood> BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway.

BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway.

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第一作者： Miriam,Butler

第一单位： Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.;Laboratory of Pediatric Oncology, Department of Pediatrics, and.

作者： Miriam,Butler ^[1] ; Dorette S,van Ingen Schenau ^[2] ; Jiangyan,Yu ^[3] ; Silvia,Jenni ^[4] ; Maria P,Dobay ^[4] ; Rico,Hagelaar ^[2] ; Britt M T,Vervoort ^[2] ; Trisha M,Tee ^[2] ; Fieke W,Hoff ^[5] ; Jules P,Meijerink ^[2] ; Steven M,Kornblau ^[6] ; Beat,Bornhauser ^[4] ; Jean-Pierre,Bourquin ^[4] ; Roland P,Kuiper ^[7] ; Laurens T,van der Meer ^[2] ; Frank N,van Leeuwen ^[2]

作者单位： Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.;Laboratory of Pediatric Oncology, Department of Pediatrics, and. ^[1] Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands. ^[2] Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.;Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands Radboud University Medical Center, Nijmegen, The Netherlands. ^[3] Department of Pediatric Oncology, Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland. ^[4] Department of Leukemia and Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX.;Department of Pediatric Oncology/Hematology, Beatrix Children's Hospital University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; and. ^[5] Department of Leukemia and Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX. ^[6] Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.;Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands. ^[7]