CD8+PD-L1+CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2-infected patients.

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作者： Lucille,Adam ^[1] ; Pierre,Rosenbaum ^[1] ; Paul,Quentric ^[1] ; Christophe,Parizot ^[2] ; Olivia,Bonduelle ^[1] ; Noëlline,Guillou ^[2] ; Aurélien,Corneau ^[1] ; Karim,Dorgham ^[1] ; Makoto,Miyara ^[3] ; Charles-Edouard,Luyt ^[1] ; Amélie,Guihot ^[1] ; Guy,Gorochov ^[2] ; Christophe,Combadière ^[4] ; Behazine,Combadière ^[5]

作者单位： Sorbonne University, Inserm U1135, Center for Immunology and Infectious Diseases, Cimi-Paris, Paris, France. ^[1] Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière University Hospital, Department of Immunology, Paris, France. ^[2] Sorbonne University, UMS037, PASS, Pitié-Salpêtrière Cytometry Platform (CyPS), Paris, France. ^[3] AP-HP, Pitié-Salpêtrière University Hospital, Department of Pulmonology, Intensive Medicine, and Resuscitation, Paris, France. ^[4] Sorbonne University, Inserm, Institute of Cardiometabolism and Nutrition, Paris, France. ^[5]

关键词 Adaptive immunity Immunology T cells

主题词成年人(Adult);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);表位, T淋巴细胞(Epitopes, T-Lymphocyte);女(雌)性(Female);法国(France);人类(Humans);免疫, 细胞(Immunity, Cellular);免疫记忆(Immunologic Memory);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);受体, CXCR3(Receptors, CXCR3);存活率(Survival Rate)

DOI 10.1172/jci.insight.151571

PMID 34283810

发布时间 2021-10-08

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2021年6卷18期

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CD8+PD-L1+CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2-infected patients.

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CD8+PD-L1+CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2-infected patients.

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