换一批A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods.
第一作者：
Charlotte Johanna,Beelen
第一单位：
Department of Neuroscience, Division of Biochemistry, University of Oldenburg, 26111 Oldenburg, Germany.
作者：
关键词
ADP, adenosine diphosphateATP, adenosine-5′-triphosphateArr, arrestinBG, background illuminationCNG, cyclic nucleotide-gated (channel)CSM, completely substituted mutant of rhodopsinCV, coefficient of variationDM, deterministic modelDynamic modelingE, effector of the phototransduction cascade, activated PDEFFT, fast Fourier-transformGC, guanylate cyclaseGCAPs, guanylate cyclase-activating proteinsGDP, guanosine-5′-diphosphateGPCR, G protein-coupled receptorGTP, guanosine-5′-triphosphateGt, G protein/transducinGα, α-subunit of the G proteinGβγ, β- and γ-subunit of the G proteinHSDM, hybrid stochastic/deterministic modelLight adaptationMPR, multiple photon responsePDE, phosphodiesterase 6Ph, photonsPhototransductionR, rhodopsinRGS, regulator of G protein signalingRK, rhodopsin kinaseROS, rod outer segmentRec, recoverinRn, activated rhodopsin that has been phosphorylated n timesSD, standard deviationSPR, single photon responseStochastic simulationSystems biologyTTP, time to peakcGMP, cyclic guanosine monophosphateΔJ, photocurrentΔU, photovoltage
DOI
10.1016/j.csbj.2021.06.033
PMID
34285774
发布时间
2021-07-22
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