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Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial.

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第一作者： Mark Krogh,Hvistendahl

第一单位： Department of Intestinal Failure and Liver Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

作者： Mark Krogh,Hvistendahl ^[1] ; Rahim Mohammad,Naimi ^[1] ; Svend Høime,Hansen ^[2] ; Jens Frederik,Rehfeld ^[2] ; Hannelouise,Kissow ^[3] ; Jens,Pedersen ^[3] ; Lars Ove,Dragsted ^[4] ; David Peick,Sonne ^[5] ; Filip Krag,Knop ^[6] ; Palle Bekker,Jeppesen ^[1]

作者单位： Department of Intestinal Failure and Liver Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. ^[1] Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. ^[2] Novo Nordisk Foundation Center of Basic Metabolic Research and Department of Biomedical Sciences, Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ^[3] Department of Nutrition, Exercise and Sports, Science, University of Copenhagen, Frederiksberg, Denmark. ^[4] Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark. ^[5] Novo Nordisk Foundation Center of Basic Metabolic Research and Department of Biomedical Sciences, Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.;Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.;Department of Clinical Medicine, Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Steno Diabetes Center Copenhagen, Gentofte, Denmark. ^[6]

关键词 7α-hydroxy-4-cholesten-3-one fibroblast growth factor 19 glucagon-like peptide-2 short bowel syndrome

医学主题词胆汁酸类和盐类(Bile Acids and Salts);成纤维细胞生长因子(Fibroblast Growth Factors);胰高血糖素样肽2(Glucagon-Like Peptide 2);人类(Humans);肝(Liver);短肠综合征(Short Bowel Syndrome)

DOI 10.1002/jpen.2224

PMID 34287979

发布时间 2022-07-20

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