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Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients.

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第一作者： Florent,Mouliere

第一单位： Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.;Cancer Research UK Major Centre - Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK.;Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pathology, Cancer Centre Amsterdam, Amsterdam, The Netherlands.

作者： Florent,Mouliere ^[1] ; Christopher G,Smith ^[2] ; Katrin,Heider ^[2] ; Jing,Su ^[2] ; Ymke,van der Pol ^[3] ; Mareike,Thompson ^[2] ; James,Morris ^[2] ; Jonathan C M,Wan ^[2] ; Dineika,Chandrananda ^[2] ; James,Hadfield ^[2] ; Marta,Grzelak ^[2] ; Irena,Hudecova ^[2] ; Dominique-Laurent,Couturier ^[2] ; Wendy,Cooper ^[2] ; Hui,Zhao ^[2] ; Davina,Gale ^[2] ; Matthew,Eldridge ^[2] ; Colin,Watts ^[4] ; Kevin,Brindle ^[2] ; Nitzan,Rosenfeld ^[2] ; Richard,Mair ^[5]

作者单位： Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.;Cancer Research UK Major Centre - Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK.;Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pathology, Cancer Centre Amsterdam, Amsterdam, The Netherlands. ^[1] Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.;Cancer Research UK Major Centre - Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK. ^[2] Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pathology, Cancer Centre Amsterdam, Amsterdam, The Netherlands. ^[3] Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. ^[4] Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.;Cancer Research UK Major Centre - Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK.;Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. ^[5]

关键词 cell-free DNA circulating tumor DNA fragmentomics gliomas liquid biopsy

医学主题词神经胶质瘤(Glioma);人类(Humans);突变(Mutation);血浆(Plasma);序列分析, DNA(Sequence Analysis, DNA)

DOI 10.15252/emmm.202012881

PMID 34291583

发布时间 2024-02-10

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