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Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.

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第一作者： Stefan,Willmann

第一单位： Research and Development, Pharmaceuticals, Bayer AG, Wuppertal/Leverkusen, Germany.

作者： Stefan,Willmann ^[1] ; Katrin,Coboeken ^[1] ; Yang,Zhang ^[1] ; Hannah,Mayer ^[1] ; Ibrahim,Ince ^[1] ; Emir,Mesic ^[2] ; Kirstin,Thelen ^[1] ; Dagmar,Kubitza ^[1] ; Anthonie W A,Lensing ^[1] ; Haitao,Yang ^[3] ; Peijuan,Zhu ^[3] ; Wolfgang,Mück ^[1] ; Henk-Jan,Drenth ^[2] ; Jörg,Lippert ^[1]

作者单位： Research and Development, Pharmaceuticals, Bayer AG, Wuppertal/Leverkusen, Germany. ^[1] Leiden Experts on Advanced Pharmacokinetics and Pharmacodynamics (LAP&P, Leiden, The Netherlands. ^[2] Janssen Research and Development, LLC, Raritan, New Jersey, USA. ^[3]

医学主题词青少年(Adolescent);儿童(Child);儿童, 学龄前(Child, Preschool);计算机模拟(Computer Simulation);女(雌)性(Female);Fontan手术(Fontan Procedure);心脏缺损, 先天性(Heart Defects, Congenital);人类(Humans);婴儿(Infant);婴儿, 新生(Infant, Newborn);男(雄)性(Male);模型, 生物学(Models, Biological);前瞻性研究(Prospective Studies);静脉血栓栓塞(Venous Thromboembolism)

DOI 10.1002/psp4.12688

PMID 34292671

发布时间 2022-03-14

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CPT: pharmacometrics & systems pharmacology

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2021年10卷10期

1195-1207页

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2021年10卷10期

1195-1207页

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Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.

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Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.

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