VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
第一作者:
Hongling,Li
第一单位:
Division of Oncology, Gansu Provincial Hospital, 204 Donggang West road, Chengguan district, Lanzhou City, 730000, Gansu Province, China. lihongling1969@126.com.
作者:
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);苯甲醛类(Benzaldehydes);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);希夫碱类(Schiff Bases);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1038/s41598-021-94388-x
PMID
34294779
发布时间
2021-11-09
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