Chemical update on the potential for serotonin 5-HT<sub>6</sub> and 5-HT<sub>7</sub> receptor agents in the treatment of Alzheimer's disease.

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作者： Katarzyna,Kucwaj-Brysz ^[1] ; Hanna,Baltrukevich ^[1] ; Kinga,Czarnota ^[1] ; Jadwiga,Handzlik ^[2]

作者单位： Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. ^[1] Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: j.handzlik@uj.edu.pl. ^[2]

关键词 5-HT(6)R antagonist 5-HT(7)-antagonist Alzheimer’s disease Cognitive impairments Procognitive activity Serotonin receptors

主题词阿尔茨海默病(Alzheimer Disease);动物(Animals);人类(Humans);脑代谢改善药(Nootropic Agents);受体, 血清素(Receptors, Serotonin);血清素拮抗药(Serotonin Antagonists);血清素受体激动剂(Serotonin Receptor Agonists)

DOI 10.1016/j.bmcl.2021.128275

PMID 34311086

发布时间 2021-12-27

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