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首页> Investigative ophthalmology & visual science> Assocation Between Leber's Hereditary Optic Neuropathy and MT-ND1 3460G>A Mutation-Induced Alterations in Mitochondrial Function, Apoptosis, and Mitophagy.

Assocation Between Leber's Hereditary Optic Neuropathy and MT-ND1 3460G>A Mutation-Induced Alterations in Mitochondrial Function, Apoptosis, and Mitophagy.

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第一作者： Juanjuan,Zhang

第一单位： School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.

作者： Juanjuan,Zhang ^[1] ; Yanchun,Ji ^[2] ; Jie,Chen ^[3] ; Man,Xu ^[4] ; Guoping,Wang ^[2] ; Xiaorui,Ci ^[2] ; Bing,Lin ^[2] ; Jun Q,Mo ^[2] ; Xiangtian,Zhou ^[1] ; Min-Xin,Guan ^[5]

作者单位： School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. ^[1] Attardi Institute of Mitochondrial Biomedicine, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China. ^[2] Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. ^[3] Division of Medical Genetics and Genomics, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China. ^[4] Department of Pathology, Rady Children's Hospital, University of California at San Diego School of Medicine, San Diego, California, United States. ^[5] Zhejiang Provincial Key Laboratory of Genetic and Developmental Disorders, Hangzhou, Zhejiang, China. ^[6]

主题词细胞凋亡(Apoptosis);细胞, 培养的(Cells, Cultured);DNA突变分析(DNA Mutational Analysis);DNA, 线粒体(DNA, Mitochondrial);女(雌)性(Female);人类(Humans);男(雄)性(Male);线粒体(Mitochondria);突变(Mutation);NADH脱氢酶(NADH Dehydrogenase);视神经萎缩, 遗传性, Leber(Optic Atrophy, Hereditary, Leber);系谱(Pedigree)

DOI 10.1167/iovs.62.9.38

PMID 34311469

发布时间 2021-10-04

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Investigative ophthalmology & visual science

Investigative ophthalmology & visual science

2021年62卷9期

38页

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2021年62卷9期

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