Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells.

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作者： Nikolai,Petrov ^[1] ; Hee-Sheung,Lee ^[1] ; Mikhail,Liskovykh ^[1] ; Marie-Paule,Teulade-Fichou ^[2] ; Hiroshi,Masumoto ^[3] ; William C,Earnshaw ^[4] ; Yves,Pommier ^[1] ; Vladimir,Larionov ^[1] ; Natalay,Kouprina ^[1]

作者单位： Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. ^[1] Chemistry and Modelling for the Biology of Cancer, CNRS UMR 9187-INSERM U1196 Institute Curie, Research Center, Campus University Paris-Saclay, Orsay, France. ^[2] Laboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, Kisarazu, Chiba 292-0818, Japan. ^[3] Wellcome Centre for Cell Biology, School of Biological Sciences, King's Buildings, University of Edinburgh, Max Born Crescent, Edinburgh EH9 3BF, Scotland. ^[4]

关键词 CIN chromosome instability human artificial chromosome platinum-derived G4-quadruplexes telomere dysfunction

DOI 10.18632/oncotarget.28020

PMID 34316326

发布时间 2021-07-29

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