Phospholipid exchange shows insulin receptor activity is supported by both the propensity to form wide bilayers and ordered raft domains.

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第一作者： Pavana,Suresh

第一单位： Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA.

作者： Pavana,Suresh ^[1] ; W Todd,Miller ^[2] ; Erwin,London ^[3]

作者单位： Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA. ^[1] Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York, USA; Department of Veterans Affairs Medical Center, Northport, New York, USA. ^[2] Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA. Electronic address: Erwin.london@stonybrook.edu. ^[3]

关键词 autophosphorylation bilayer width cyclodextrin insulin insulin receptor lipid exchange lipid rafts liquid ordered membrane lipid membrane structure

主题词动物(Animals);CHO细胞(CHO Cells);仓鼠属(Cricetulus);脂双层(Lipid Bilayers);膜微区(Membrane Microdomains);磷脂类(Phospholipids);受体, 胰岛素(Receptor, Insulin)

DOI 10.1016/j.jbc.2021.101010

PMID 34324831

发布时间 2021-11-22

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