Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function.

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第一作者： Siddhartha S,Saha

第一单位： Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.

作者： Siddhartha S,Saha ^[1] ; Nyssa B,Samanas ^[1] ; Irina,Miralda ^[1] ; Nicholas J,Shubin ^[1] ; Kerri,Niino ^[1] ; Gauri,Bhise ^[1] ; Manasa,Acharya ^[1] ; Albert J,Seo ^[1] ; Nathan,Camp ^[1] ; Gail H,Deutsch ^[2] ; Richard G,James ^[3] ; Adrian M,Piliponsky ^[4]

作者单位： Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash. ^[1] Department of Laboratories, Seattle Children's Research Institute, Seattle, Wash; Department of Pathology, University of Washington School of Medicine, Seattle, Wash. ^[2] Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash. ^[3] Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Department of Pathology, University of Washington School of Medicine, Seattle, Wash; Department of Global Health, University of Washington School of Medicine, Seattle, Wash. Electronic address: adrian.piliponsky@seattlechildrens.org. ^[4]

关键词 CD98hc CRISPR/Cas9 Mast cells glycoprotein enrichment mass spectrometry surfaceome

主题词动物(Animals);细胞, 培养的(Cells, Cultured);肥大细胞(Mast Cells);膜蛋白质类(Membrane Proteins);小鼠(Mice);蛋白质组(Proteome)

DOI 10.1016/j.jaci.2021.07.014

PMID 34324892

发布时间 2023-02-10

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