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COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy.

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第一作者: Markus,Weckmann
第一单位: Division of Pediatric Pneumology and Allergology, University Medical Center Schleswig-Holstein, Lübeck, Germany markus.weckmann@uksh.de.;Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany.
作者单位: Division of Pediatric Pneumology and Allergology, University Medical Center Schleswig-Holstein, Lübeck, Germany markus.weckmann@uksh.de.;Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany. [1] Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany.;Dept of Pneumology, LungenClinic Grosshansdorf, Grosshansdorf, Germany. [2] Nordic Bioscience A/S, Herlev, Denmark. [3] Nordic Bioscience A/S, Herlev, Denmark.;University of Southern Denmark, The Faculty of Health Science, Odense, Denmark. [4] Division of Pediatric Pneumology and Allergology, University Medical Center Schleswig-Holstein, Lübeck, Germany.;Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany. [5] University of Groningen, University Medical Center Groningen, Dept of Pulmonary Diseases, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, The Netherlands. [6] University of Groningen, University Medical Center Groningen, Dept of Pulmonary Diseases, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, The Netherlands.;University of Groningen, University Medical Center Groningen, Dept of Pathology and Medical Biology, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, The Netherlands.;Woolcock Institute of Medical Research, The University of Sydney, Glebe, Australia.;School of Medical and Molecular Biosciences, University of Technology, Sydney, Australia. [7] University of Southern Denmark, The Faculty of Health Science, Odense, Denmark. [8] Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany.;Division of Asthma-Exacerbation and -Regulation, Program Area Asthma and Allergy, Leibniz-Center for Medicine and Biosciences Borstel, Borstel, Germany. [9] Woolcock Institute of Medical Research, The University of Sydney, Glebe, Australia.;School of Medical and Molecular Biosciences, University of Technology, Sydney, Australia. [10] AG Synergyresearch and Experimental Medicine, Medical Clinic III, University Hospital Bonn, Bonn, Germany. [11] Dept of Pneumonology, Medical Clinic II, University Hospital Bonn, Bonn, Germany. [12] Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany. [13] Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany. [14] Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, German Research Center for Environmental Health (CPC-M), Member of the German Center of Lung Research (DZL), Munich, Germany. [15] University of Groningen, University Medical Center Groningen, Dept of Pulmonary Diseases, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, The Netherlands.;University of Groningen, University Medical Center Groningen, Dept of Pathology and Medical Biology, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, The Netherlands. [16] Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany.;Institute for Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany. [17] Dept of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.;Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center of Lung Research (DZL), Germany. [18] University Children's Hospital, Ludwig Maximilian's University, Munich, Germany.;German Research Center for Environmental Health (CPC-M), Member of the German Center of Lung Research (DZL), Munich, Germany. [19] Division of Pediatric Pneumology and Allergology, University Medical Center Schleswig-Holstein, Lübeck, Germany.;Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Germany.;Dept of Paediatric Respiratory Medicine, Inselspital, University Children's Hospital of Bern, University of Bern, Bern, Switzerland. [20] University of Groningen, University Medical Center Groningen, Dept of Pathology and Medical Biology, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, The Netherlands.;Woolcock Institute of Medical Research, The University of Sydney, Glebe, Australia.;Discipline of Pharmacology, Faculty of Medicine, The University of Sydney, Sydney, Australia. [21]
DOI 10.1183/13993003.03969-2020
PMID 34326188
发布时间 2022-05-31
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The European respiratory journal

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