pH-Responsive STING-Activating DNA Nanovaccines for Cancer Immunotherapy.

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第一作者： Yu,Zhang

第一单位： Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Department of Pharmaceutics, Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23219, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23219, USA; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA.

作者： Yu,Zhang ^[1] ; Tingting,Shen ^[2] ; Shurong,Zhou ^[3] ; Weinan,Wang ^[3] ; Shuibin,Lin ^[4] ; Guizhi,Zhu ^[3]

作者单位： Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Department of Pharmaceutics, Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23219, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23219, USA; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA. ^[1] Department of Pharmaceutics, Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23219, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23219, USA; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA; Molecular Sciences and Biomedicine Laboratory, State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Collaborative Innovation Center for Molecular Engineering and Theranostics, Hunan University, Changsha 410082, China. ^[2] Department of Pharmaceutics, Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23219, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23219, USA; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA. ^[3] Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. ^[4]

关键词 DNA engineering STING agonists cancer immunotherapy i-motif nanovaccines

DOI 10.1002/adtp.202000083

PMID 34337143

发布时间 2023-11-07

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Advanced therapeutics

2020年3卷9期

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