首页> EMBO reports> Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control.

Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control.

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第一作者： Alessio,Reggio

第一单位： Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.

作者： Alessio,Reggio ^[1] ; Viviana,Buonomo ^[1] ; Rayene,Berkane ^[2] ; Ramachandra M,Bhaskara ^[3] ; Mariana,Tellechea ^[4] ; Ivana,Peluso ^[1] ; Elena,Polishchuk ^[1] ; Giorgia,Di Lorenzo ^[1] ; Carmine,Cirillo ^[1] ; Marianna,Esposito ^[1] ; Adeela,Hussain ^[5] ; Antje K,Huebner ^[5] ; Christian A,Hübner ^[5] ; Carmine,Settembre ^[1] ; Gerhard,Hummer ^[6] ; Paolo,Grumati ^[1] ; Alexandra,Stolz ^[2]

作者单位： Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy. ^[1] Institute of Biochemistry II (IBC2), Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.;Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany. ^[2] Institute of Biochemistry II (IBC2), Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.;Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany.;Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany. ^[3] Institute of Biochemistry II (IBC2), Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.;Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany.;Structural Genomics Consortium at BMLS, Goethe University, Frankfurt am Main, Germany. ^[4] Institute of Human Genetics, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany. ^[5] Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.;Institute for Biophysics, Goethe University, Frankfurt am Main, Germany. ^[6]

关键词 Collagen ER stress ER-phagy FAM134 autophagy

医学主题词自噬(Autophagy);胶原(Collagen);内质网(Endoplasmic Reticulum);膜蛋白质类(Membrane Proteins);蛋白质组学(Proteomics);质量控制(Quality Control)

DOI 10.15252/embr.202052289

PMID 34338405

发布时间 2026-06-12

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