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Homozygous mutations in <i>CCDC34</i> cause male infertility with oligoasthenoteratozoospermia in humans and mice.

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作者单位: Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute for Biomedical and Pharmaceutical Technologies), State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China. [1] Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, China. [2] Department of Surgery, Medical College of Shandong University, Jinan, Shandong, China. [3] Reproductive Medicine Center, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China. [4] Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, Academic Center for Education, Culture, and Research, Tehran, Iran. [5] Université Grenoble Alpes, Genetic Epigenetic and Therapies of Infertility, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Grenoble, France. [6] Centre Hospitalier Universitaire de Grenoble, UM GI-DPI, Grenoble, France. [7] Laboratoire Eurofins Biomnis, Lyon, France. [8] Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, Academic Center for Education, Culture, and Research, Tehran, Iran. [9] State Key Laboratory of Reproductive Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, China. [10] Suzhou Municipal Hospital, Suzhou, Jiangsu, China. [11] Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. [12] NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China. [13] MOE Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Hefei, Anhui, China. [14] State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China. [15] University of the Chinese Academy of Sciences, Shangai, China. [16] Université Grenoble Alpes, Genetic Epigenetic and Therapies of Infertility, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Grenoble, France zhangfeng@fudan.edu.cn pray@chu-grenoble.fr. [17] Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute for Biomedical and Pharmaceutical Technologies), State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China zhangfeng@fudan.edu.cn pray@chu-grenoble.fr. [18]
DOI 10.1136/jmedgenet-2021-107919
PMID 34348960
发布时间 2022-09-07
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Journal of medical genetics

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