Dual targeting of CTLA-4 and CD47 on T<sub>reg</sub> cells promotes immunity against solid tumors.

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作者： Anli,Zhang ^[1] ; Zhenhua,Ren ^[1] ; Kuo-Fu,Tseng ^[2] ; Xiaojuan,Liu ^[3] ; Huiyu,Li ^[4] ; Changzheng,Lu ^[1] ; Yueqi,Cai ^[3] ; John D,Minna ^[4] ; Yang-Xin,Fu ^[5]

作者单位： Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA. ^[1] Aetio Biotherapy, Dallas, TX 75247, USA. ^[2] Chinese Academy of Sciences Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. ^[3] Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, TX 75390, USA. ^[4] Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA. yang-xin.fu@utsouthwestern.edu. ^[5]

主题词动物(Animals);小鼠(Mice);肿瘤(Neoplasms);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);肿瘤微环境(Tumor Microenvironment)

DOI 10.1126/scitranslmed.abg8693

PMID 34349035

发布时间 2023-06-02

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准确一般字义偏差语意偏离译文作用小提交