The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis.

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第一作者： Amanda J,Morris

第一单位： Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.

作者： Amanda J,Morris ^[1] ; Lindsay,Jackson ^[1] ; Yvonne,Cw Yau ^[2] ; Courtney,Reichhardt ^[3] ; Trevor,Beaudoin ^[1] ; Stephanie,Uwumarenogie ^[1] ; Kevin M,Guttman ^[1] ; P,Lynne Howell ^[4] ; Matthew R,Parsek ^[5] ; Lucas R,Hoffman ^[3] ; Dao,Nguyen ^[6] ; Antonio,DiGiandomenico ^[7] ; David S,Guttman ^[8] ; Daniel J,Wozniak ^[9] ; Valerie J,Waters ^[10]

作者单位： Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada. ^[1] Division of Microbiology, Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. ^[2] Department of Microbiology, University of Washington, Seattle, WA, USA. ^[3] Program in Molecular Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada. ^[4] Department of Biochemistry, University of Toronto, Toronto, ON, Canada. ^[5] Departments of Pediatrics and Microbiology, University of Washington, Seattle, WA, USA. ^[6] Department of Medicine, McGill University, Montreal, QC, Canada. ^[7] Discovery Microbiome, Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, USA. ^[8] Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada. ^[9] Departments of Microbial Infection and Immunity, Microbiology, Ohio State University, Columbus, OH, USA. ^[10] Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada. Valerie.waters@sickkids.ca. ^[11] Division of Infectious Diseases, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada. Valerie.waters@sickkids.ca. ^[12] Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Valerie.waters@sickkids.ca. ^[13]

主题词黏着素, 细菌(Adhesins, Bacterial);抗菌药(Anti-Bacterial Agents);抗体, 细菌(Antibodies, Bacterial);抗原, 细菌(Antigens, Bacterial);细菌蛋白质类(Bacterial Proteins);生物膜(Biofilms);儿童(Child);囊性纤维化(Cystic Fibrosis);人类(Humans);假单胞菌感染(Pseudomonas Infections);铜绿假单胞菌(Pseudomonas aeruginosa);呼吸系统(Respiratory System);妥布拉霉素(Tobramycin)

DOI 10.1038/s41522-021-00234-3

PMID 34349133

发布时间 2022-05-12

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NPJ biofilms and microbiomes

2021年7卷1期

63页

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The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis.

NPJ biofilms and microbiomes

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The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis.

NPJ biofilms and microbiomes

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NPJ biofilms and microbiomes

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