Inhibition of WEE1 Potentiates Sensitivity to PARP Inhibitor in Biliary Tract Cancer.

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第一作者： Hye-Rim,Seo

第一单位： Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.;Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, Korea.

作者： Hye-Rim,Seo ^[1] ; Ah-Rong,Nam ^[2] ; Ju-Hee,Bang ^[2] ; Kyoung-Seok,Oh ^[2] ; Jae-Min,Kim ^[1] ; Jeesun,Yoon ^[3] ; Tae-Yong,Kim ^[4] ; Do-Youn,Oh ^[5]

作者单位： Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.;Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, Korea. ^[1] Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ^[2] Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. ^[3] Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.;Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. ^[4] Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.;Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, Korea.;Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. ^[5]

关键词 Biliary tract neoplasms Cell cycle checkpoint DNA damage response Homologous recombination Poly(ADP-ribose) polymerase WEE1