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The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer.

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第一作者： Barbara,Melosky

第一单位： Medical Oncology, BCCA - 600 W 10th Ave, Vancouver, BC, V5Z 4E6, Canada. Electronic address: BMelosky@bccancer.bc.ca.

作者： Barbara,Melosky ^[1] ; Paul,Wheatley-Price ^[2] ; Rosalyn A,Juergens ^[3] ; Adrian,Sacher ^[4] ; Natasha B,Leighl ^[5] ; Ming-Sound,Tsao ^[4] ; Parneet,Cheema ^[6] ; Stephanie,Snow ^[7] ; Geoffrey,Liu ^[4] ; Paul B,Card ^[8] ; Quincy,Chu ^[9]

作者单位： Medical Oncology, BCCA - 600 W 10th Ave, Vancouver, BC, V5Z 4E6, Canada. Electronic address: BMelosky@bccancer.bc.ca. ^[1] Ottawa Hospital Research Institute, University of Ottawa, 501 Smyth Box 511, Ottawa, ON, K1H 8L6, Canada. ^[2] Juravinski Cancer Centre, McMaster University, 699 Concession Street, Hamilton, ON, L8V5C2, Canada. ^[3] Princess Margaret Cancer Centre, University of Toronto, 101 College Street, Toronto, ON, M5G1L7, Canada. ^[4] Princess Margaret Cancer Centre, University of Toronto, 7-913 700 University Avenue, Toronto, ON, M5G1Z5, Canada. ^[5] William Osler Health System, University of Toronto, 101 Humber College Blvd, Etobicoke, ON, M9V 1R8, Canada. ^[6] QEII Health Sciences Centre, Dalhousie University, 1276 South Park Street Halifax, NS, B3H 2Y9, Canada. ^[7] Kaleidoscope Strategic Inc., 146 Marion St., Toronto, ON, M6R 1E7, Canada. ^[8] Cross Cancer Institute, University of Alberta, 11560 University Ave, 2nd Floor, Edmonton, AB, T6G 1Z2, Canada. ^[9]

关键词 Antibody drug conjugate Carcinoma, non-small-cell lung Gene amplification Gene rearrangement Molecular targeted therapy Oncogene fusion Oncogene proteins Oncogenes Point mutation Protein kinase inhibitors

医学主题词癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);人类(Humans);肺肿瘤(Lung Neoplasms);分子靶向治疗(Molecular Targeted Therapy);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);原癌基因蛋白质类(Proto-Oncogene Proteins)

DOI 10.1016/j.lungcan.2021.06.002

PMID 34353680

发布时间 2021-10-22

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准确一般字义偏差语意偏离译文作用小提交