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首页> Journal of psychiatric research> A novel commentary: Investigation of the role of a balance between neurotrophic and apoptotic proteins in the pathogenesis of psychosis via the tPA-BDNF pathway.

A novel commentary: Investigation of the role of a balance between neurotrophic and apoptotic proteins in the pathogenesis of psychosis via the tPA-BDNF pathway.

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作者： Umit Haluk,Yesilkaya ^[1] ; Sakir,Gica ^[2] ; Busra,Guney Tasdemir ^[3] ; Pelin,Ozkara Menekseoglu ^[3] ; Zeynep,Cirakli ^[4] ; Nesrin,Karamustafalioglu ^[3]

作者单位： Department of Psychiatry, Bakirkoy Prof Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey. Electronic address: u.yesilkaya@saglik.gov.tr. ^[1] Department of Psychiatry, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey. ^[2] Department of Psychiatry, Bakirkoy Prof Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey. ^[3] Department of Biochemistry Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey. ^[4]

关键词 Apoptosis BDNF Neurotrophin Schizophrenia Synaptic pruning proBDNF

主题词脑源性神经营养因子(Brain-Derived Neurotrophic Factor);病例对照研究(Case-Control Studies);人类(Humans);膜糖蛋白类(Membrane Glycoproteins);神经组织蛋白质类(Nerve Tissue Proteins);纤溶酶原激活物抑制物1(Plasminogen Activator Inhibitor 1);精神病(Psychotic Disorders);受体, trkB(Receptor, trkB);受体, 神经生长因子类(Receptors, Nerve Growth Factor);组织型纤溶酶原激活物(Tissue Plasminogen Activator)

DOI 10.1016/j.jpsychires.2021.07.056

PMID 34359010

发布时间 2022-05-31

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Journal of psychiatric research

160-166页

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