Developing potency factors for thyroid hormone disruption by PFASs using TTR-TRβ CALUX® bioassay and assessment of PFASs mixtures in technical products.

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作者： Peter A,Behnisch ^[1] ; Harrie,Besselink ^[1] ; Roland,Weber ^[2] ; Wolfram,Willand ^[3] ; Jun,Huang ^[4] ; Abraham,Brouwer ^[5]

作者单位： BioDetection Systems B.V. (BDS), Science Park 406, 1098 XH Amsterdam, the Netherlands. ^[1] POPs Environmental Consulting, Lindenfirststrasse 23, 73527 Schwäbisch Gmünd, Germany. ^[2] IUW International Consultant on Integrated Environmental Protection and POPs, Hochfirstweg 12, 79853 Lenzkirch, Germany. ^[3] State Key Joint Laboratory of Environment Simulation and Pollution Control (SKLESPC), Beijing Key Laboratory for Emerging Organic Contaminants Control (BKLEOC), Beijing Laboratory for Environmental Frontier Technologies (BLEFT), School of Environment, Tsinghua University, Beijing 100084, China. ^[4] BioDetection Systems B.V. (BDS), Science Park 406, 1098 XH Amsterdam, the Netherlands; VU University Amsterdam, Faculty of Sciences, Department of Animal Ecology, De Boelelaan 1085, 1081 HV Amsterdam, the Netherlands. Electronic address: bram.brouwer@bds.nl. ^[5]

关键词 Aqueous film-forming foams/Aqueous fire-fighting foams (AFFF)Bioassay Chromium mist suppressants (CMS)Endocrine disrupting chemicals Per- and polyfluoroalkyl substances (PFASs)TTR-TRβ CALUX?Thyroid hormone

主题词链烷磺酸类(Alkanesulfonic Acids);生物学鉴定法(Biological Assay);氟碳化合物(Fluorocarbons);甲状腺激素受体β(Thyroid Hormone Receptors beta);甲状腺激素类(Thyroid Hormones);水污染物, 化学性(Water Pollutants, Chemical)

DOI 10.1016/j.envint.2021.106791

PMID 34364217

发布时间 2021-10-18

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