Induction and expansion of human PRRX1<sup>+</sup> limb-bud-like mesenchymal cells from pluripotent stem cells.

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第一作者： Daisuke,Yamada

第一单位： Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

作者： Daisuke,Yamada ^[1] ; Masahiro,Nakamura ^[2] ; Tomoka,Takao ^[1] ; Shota,Takihira ^[1] ; Aki,Yoshida ^[3] ; Shunsuke,Kawai ^[3] ; Akihiro,Miura ^[4] ; Lu,Ming ^[1] ; Hiroyuki,Yoshitomi ^[1] ; Mai,Gozu ^[4] ; Kumi,Okamoto ^[5] ; Hironori,Hojo ^[5] ; Naoyuki,Kusaka ^[5] ; Ryosuke,Iwai ^[6] ; Eiji,Nakata ^[7] ; Toshifumi,Ozaki ^[7] ; Junya,Toguchida ^[3] ; Takeshi,Takarada ^[3]

作者单位： Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. ^[1] Precision Health, Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. ^[2] Department Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. ^[3] Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan. ^[4] Department of Regeneration Science and Engineering, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan. ^[5] Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ^[6] Institute of Frontier Science and Technology, Okayama University of Science, Okayama, Japan. ^[7] Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. takarada@okayama-u.ac.jp. ^[8]

主题词动物(Animals);细胞培养技术(Cell Culture Techniques);细胞分化(Cell Differentiation);软骨细胞(Chondrocytes);软骨发生(Chondrogenesis);胶原病(Collagen Diseases);培养基(Culture Media);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);间质干细胞(Mesenchymal Stem Cells);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);多潜能干细胞(Pluripotent Stem Cells);聚合物(Polymers);受体, 血小板源生长因子β(Receptor, Platelet-Derived Growth Factor beta);组织工程(Tissue Engineering)

DOI 10.1038/s41551-021-00778-x

PMID 34373601

发布时间 2023-02-03

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Nature biomedical engineering

2021年5卷8期

926-940页

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Induction and expansion of human PRRX1<sup>+</sup> limb-bud-like mesenchymal cells from pluripotent stem cells.

Nature biomedical engineering

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Induction and expansion of human PRRX1<sup>+</sup> limb-bud-like mesenchymal cells from pluripotent stem cells.

Nature biomedical engineering

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Nature biomedical engineering

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