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Evidence generation and reproducibility in cell and gene therapy research: A call to action.

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第一作者: Mohamed,Abou-El-Enein
第一单位: Division of Medical Oncology, Department of Medicine and Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
作者单位: Division of Medical Oncology, Department of Medicine and Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. [1] Joint USC/CHLA Cell Therapy Program, University of Southern California and Children's Hospital Los Angeles, Los Angeles, CA, USA. [2] Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK. [3] Department of Health Policy and LSE Health, London School of Economics and Political Science, London, UK. [4] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. [5] Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, USA. [6] Department of Pharmacology and Cancer Biology and Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA. [7] Department of Medicine, Division of Hematology/Oncology, Columbia University Irving Medical Center, New York, NY, USA. [8] Center for Evidence and Practice Improvement, Agency for Healthcare Research and Quality, Rockville, MD, USA. [9] Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA. [10] Biotherapy Department, Necker Children's Hospital, Assistance Publique-Hopitaux de Paris, Paris, France. [11] Biotherapy Clinical Investigation Center, Groupe Hospitalier Universitaire Quest, INSERM, Paris, France. [12] Hematologic Malignancies and Stem Cell Transplantation Institute, City of Hope National Medical Center, Duarte, CA, USA. [13] Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands. [14] University Medical Center Utrecht, Utrecht, the Netherlands. [15] European Medicines Agency, Amsterdam, the Netherlands. [16] Boston Children's Hospital, Boston, MA, USA. [17] Harvard Medical School, Boston, MA, USA. [18] US National Academy of Medicine, Washington, DC, USA. [19] Department of Surgical Oncology and Molecular & Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [20] Gordon and Betty Moore Foundation, Palo Alto, CA, USA. [21] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA. [22] Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA. [23] Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA. [24] American Association for the Advancement of Science (AAAS), Washington, DC, USA. [25] National Academy of Medicine, Washington, DC, USA. [26] Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. [27] Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA. [28] Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. [29] The Eli & Edith Broad Center of Regenerative Medicine & Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA. [30] Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. [31] Massachusetts General Hospital Cancer Center, Charlestown, MA, USA. [32] Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA. [33] Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, the Netherlands. [34] ENMED, Colleges of Medicine and Engineering, Texas A&M University, Houston, TX, USA. [35] National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. [36] Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. [37] Theory of Condensed Matter, Cavendish Laboratory, University of Cambridge, JJ Thomson Ave, Cambridge, UK. [38] Center for Regenerative Medicine, Mayo Clinic, Rochester, MN, USA. [39] Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. [40] Innovative Genomics Institute, University of California, Berkeley, CA, USA. [41] Division of Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA. [42] Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. [43] Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. [44] Patrick G Johnston Centre for Cancer Research, Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, UK. [45] Institute for Regenerative Cures, University of California, Davis, Sacramento, CA, USA. [46] Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, CA, USA. [47] Department of Epidemiology and Population Health and Department of Biomedical Data Sciences, Stanford University, Stanford, CA, USA. [48]
DOI 10.1016/j.omtm.2021.06.012
PMID 34377737
发布时间 2024-04-04
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Molecular therapy. Methods & clinical development

2021年22卷

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