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A survey of functional dyspepsia in 361,360 individuals: Phenotypic and genetic cross-disease analyses.

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第一作者： Koldo,Garcia-Etxebarria

第一单位： Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastian, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd, Madrid, Spain.;Center for Molecular Medicine and Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

作者： Koldo,Garcia-Etxebarria ^[1] ; Florencia,Carbone ^[2] ; Maris,Teder-Laving ^[3] ; Anita,Pandit ^[4] ; Lieselot,Holvoet ^[2] ; Vincent,Thijs ^[5] ; Robin,Lemmens ^[6] ; Luis,Bujanda ^[7] ; Andre,Franke ^[8] ; Sebastian,Zöllner ^[9] ; Michael,Boehnke ^[4] ; Matthew,Zawistowski ^[4] ; Tonu,Esko ^[3] ; Tack,Jan ^[2] ; Mauro,D'Amato ^[10]

作者单位： Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastian, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd, Madrid, Spain.;Center for Molecular Medicine and Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden. ^[1] Translational Research Center for GI Disorders (TARGID), University of Leuven, Leuven, Belgium. ^[2] Estonian Genome Center, University of Tartu, Tartu, Estonia. ^[3] Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA. ^[4] Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia. ^[5] Department of Neurosciences, Leuven Brain Institute (LBI), University of Leuven, Leuven, Belgium. ^[6] Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastian, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd, Madrid, Spain.;Universidad del País Vasco (UPV/EHU), San Sebastián, Spain. ^[7] Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany. ^[8] Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.;Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA. ^[9] Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastian, Spain.;Center for Molecular Medicine and Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.;IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.;Gastrointestinal Genetics Lab, CIC bioGUNE - BRTA, Derio, Spain. ^[10]

关键词 biobank studies comorbidities functional dyspepsia genetics genome-wide association study

医学主题词交叉, 遗传(Crosses, Genetic);消化不良(Dyspepsia);胃肠疾病(Gastrointestinal Diseases);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans)

DOI 10.1111/nmo.14236

PMID 34378841

发布时间 2025-05-30

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