The combination of dextran sulphate and polyvinyl alcohol prevents excess aggregation and promotes proliferation of pluripotent stem cells in suspension culture.

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第一作者： Xianglian,Tang

第一单位： School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, China.;Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences and School of Medicine, South China University of Technology, Guangzhou, China.

作者： Xianglian,Tang ^[1] ; Haibin,Wu ^[2] ; Jinghe,Xie ^[1] ; Ning,Wang ^[1] ; Qicong,Chen ^[1] ; Zhiyong,Zhong ^[1] ; Yaqi,Qiu ^[2] ; Jue,Wang ^[2] ; Xiajing,Li ^[3] ; Ping,Situ ^[2] ; Liangxue,Lai ^[4] ; Mark A,Zern ^[5] ; Honglin,Chen ^[6] ; Yuyou,Duan ^[6]

作者单位： School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, China.;Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences and School of Medicine, South China University of Technology, Guangzhou, China. ^[1] Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences and School of Medicine, South China University of Technology, Guangzhou, China. ^[2] Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China. ^[3] Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. ^[4] Department of Internal Medicine, University of California Davis Medical Center, Sacramento, CA, USA. ^[5] Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences and School of Medicine, South China University of Technology, Guangzhou, China.;National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, China.;Key Laboratory of Biomedical Engineering of Guangdong Province, South China University of Technology, Guangzhou, China.;Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education, South China University of Technology, Guangzhou, China.;Innovation Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, China. ^[6]

关键词 cell aggregates dextran sulphate human pluripotent stem cells polyvinyl alcohol spinner flask suspension culture