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Gene Expression Analysis in Three Posttraumatic Stress Disorder Cohorts Implicates Inflammation and Innate Immunity Pathways and Uncovers Shared Genetic Risk With Major Depressive Disorder.

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第一作者： Melanie E,Garrett

第一单位： Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, United States.

作者： Melanie E,Garrett ^[1] ; Xue Jun,Qin ^[1] ; Divya,Mehta ^[2] ; Michelle F,Dennis ^[3] ; Christine E,Marx ^[3] ; Gerald A,Grant ^[4] ; VA Mid-Atlantic MIRECC Workgroup ^[5] ; PTSD Initiative ^[3] ; Injury and Traumatic Stress (INTRuST) Clinical Consortium ^[3] ; Psychiatric Genomics Consortium PTSD Group ^[1] ; Murray B,Stein ^[1] ; Nathan A,Kimbrel ; Jean C,Beckham ; Michael A,Hauser ; Allison E,Ashley-Koch

作者单位： Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, United States. ^[1] Queensland University of Technology, Centre for Genomics and Personalised Health, Faculty of Health, Institute of Health and Biomedical Innovation, Kelvin Grove, QLD, Australia. ^[2] Durham Veterans Affairs Health Care System, Durham, NC, United States.;VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC United States.;Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States. ^[3] Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, United States. ^[4] Department of Psychiatry, School of Medicine, University of California, San Diego, La Jolla, CA, United States.;Herbert Wertheim School of Public Health, University of California, San Diego, La Jolla, CA, United States.;VA San Diego Healthcare System, San Diego, CA, United States. ^[5]

关键词 gene expression major depressive disorder meta-analysis multi-ethnic posttraumatic stress disorder quantitative trait loci

DOI 10.3389/fnins.2021.678548

PMID 34393704

发布时间 2025-01-10

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