7,8-dihydroxyflavone-functionalized gold nanoparticles target the arginase enzyme of <i>Leishmania donovani</i>.

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作者： Pragya,Prasanna ^[1] ; Prakash,Kumar ^[1] ; Saptarshi,Mandal ^[2] ; Tanvi,Payal ^[1] ; Saurabh,Kumar ^[3] ; Sk Ugir,Hossain ^[1] ; Prolay,Das ^[4] ; V,Ravichandiran ^[2] ; Debabrata,Mandal ^[1]

作者单位： Department of Biotechnology, National Institute of Pharmaceutical Education & Research (NIPER), Hajipur, 844102, India. ^[1] Department of Chemistry, Indian Institute of Technology, Patna, 801106, India. ^[2] Cognizant Technology Solution, Hyderabad, 800051, India. ^[3] Department of Clinical and Translational Medicine, Chittaranjan National Cancer Institute, Kolkata, 700026, India. ^[4] National Institute of Pharmaceutical Education & Research (NIPER), Kolkata, 700054, India. ^[5]

关键词 DHF DHF-GNP arginase inhibition drug-resistant parasite gold nanoparticle iNOS

主题词精氨酸酶(Arginase);黄酮类(Flavones);金(Gold);杜氏利什曼原虫(Leishmania donovani);金属纳米粒子(Metal Nanoparticles)

DOI 10.2217/nnm-2021-0161

PMID 34397295

发布时间 2021-09-02

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