Impact of repeated co-treatment with escitalopram and aripiprazole on the schizophrenia-like behaviors and BDNF mRNA expression in the adult Sprague-Dawley rats exposed to glutathione deficit during early postnatal development of the brain.

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作者： Marta A,Lech ^[1] ; Kinga,Kamińska ^[1] ; Monika,Leśkiewicz ^[2] ; Elżbieta,Lorenc-Koci ^[3] ; Zofia,Rogóż ^[4]

作者单位： Department of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, Kraków, Poland. ^[1] Department of Experimental Neuroendocrinology, Maj Institute of Pharmacology, Polish Academy of Sciences,, 12 Smętna Street, Kraków, Poland. ^[2] Department of Neuropsychopharmacology, Maj Institute of Pharmacology Polish Academy of Sciences, 12 Smętna Street, Kraków, Poland. ^[3] Department of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, Kraków, Poland. rogoz@if-pan.krakow.pl. ^[4] The Podhale State Higher Vocational School, Faculty of Cosmetology, Institute of Health, 71 Kokoszków, Nowy Targ, Poland. rogoz@if-pan.krakow.pl. ^[5]

关键词 Aripiprazole BDNF mRNA expression Escitalopram Novel object recognition test Schizophrenia and glutathione deficit Social interaction test