Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria.-论文-万方医学网

第一作者： Damanpreet,Garcha

第一单位： The Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, VIC, 3084, Australia.

作者： Damanpreet,Garcha ^[1] ; Susan P,Walker ^[1] ; Teresa M,MacDonald ^[2] ; Jon,Hyett ^[1] ; Jessica,Jellins ^[2] ; Jenny,Myers ^[3] ; Sebastian E,Illanes ^[3] ; Jhy K,Nien ^[4] ; Manuel,Schepeler ^[5] ; Emerson,Keenan ^[6] ; Carole-Anne,Whigham ^[6] ; Ping,Cannon ^[6] ; Elizabeth,Murray ^[1] ; Tuong-Vi,Nguyen ^[1] ; Manju,Kandel ^[2] ; Joshua,Masci ^[1] ; Ciara,Murphy ^[2] ; Tess,Cruickshank ^[1] ; Natasha,Pritchard ^[2] ; Natalie J,Hannan ^[1] ; Fiona,Brownfoot ^[2] ; Alexandra,Roddy Mitchell ^[1] ; Anna,Middleton ^[2] ; Gabrielle,Pell ^[1] ; Georgia P,Wong ^[2] ; Stephen,Tong ^[1] ; Tu'uhevaha J,Kaitu'u-Lino ^[1]

作者单位： The Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, VIC, 3084, Australia. ^[1] Mercy Perinatal, Mercy Hospital for Women, 163 Studley Road, Heidelberg, VIC, 3084, Australia. ^[2] Sydney Institute for Women, Children and Their Families, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW, 2050, Australia. ^[3] University of Manchester, Manchester Academic Health Science Centre, St Mary's Hospital, Manchester, M13 OJH, UK. ^[4] Department of Obstetrics and Gynaecology and Laboratory of Reproductive Biology, Faculty of Medicine, Universidad de Los Andes, San Carlos de Apoquindo 2200, Las Condes, Santiago de Chile, Chile. ^[5] Department of Obstetrics and Gynaecology, Clínica Davila, Recoleta 464, Recoleta, Santiago, Chile. ^[6] The Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, VIC, 3084, Australia. t.klino@unimelb.edu.au. ^[7] Mercy Perinatal, Mercy Hospital for Women, 163 Studley Road, Heidelberg, VIC, 3084, Australia. t.klino@unimelb.edu.au. ^[8]

主题词成年人(Adult);曲线下面积(Area Under Curve);出生体重(Birth Weight);细胞低氧(Cell Hypoxia);接生, 产科(Delivery, Obstetric);糖尿病, 妊娠(Diabetes, Gestational);电子转运(Electron Transport);女(雌)性(Female);胎儿生长迟缓(Fetal Growth Retardation);孕龄(Gestational Age);人类(Humans);高血压(Hypertension);婴儿, 新生(Infant, Newborn);婴儿, 小于胎龄(Infant, Small for Gestational Age);基质金属蛋白酶类(Matrix Metalloproteinases);二甲双胍(Metformin);线粒体(Mitochondria);器官测量(Organ Size);超重(Overweight);胎盘(Placenta);先兆子痫(Pre-Eclampsia);妊娠(Pregnancy);妊娠并发症(Pregnancy Complications);ROC曲线(ROC Curve);吸烟(Smoking);多配体蛋白聚糖1(Syndecan-1);滋养层(Trophoblasts)

DOI 10.1038/s41598-021-96077-1

PMID 34400721

发布时间 2021-11-15

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Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria.

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Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria.

Scientific reports

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Scientific reports

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