PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells.

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第一作者： Wei,Tang

第一单位： Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

作者： Wei,Tang ^[1] ; Yu,Wu ^[1] ; Xin,Qi ^[1] ; Rilei,Yu ^[1] ; Zhimin,Lu ^[2] ; Ao,Chen ^[1] ; Xinglong,Fan ^[3] ; Jing,Li ^[4]

作者单位： Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. ^[1] Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease of the First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University, Hangzhou 310029, China. ^[2] Department of Thoracic Surgery, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao 266003, China. ^[3] Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.;Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266003, China.;Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266003, China. ^[4]

关键词 Glycogen synthase kinase-3β (GSK3β)breast cancer stem cell heat shock protein 90 (Hsp90)hsp90 inhibitors phosphoglycerate kinase 1 (PGK1)

DOI 10.20892/j.issn.2095-3941.2020.0362

PMID 34403222

发布时间 2024-02-20

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PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells.

Cancer biology & medicine

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Cancer biology & medicine

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PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells.

Cancer biology & medicine

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Cancer biology & medicine

相关期刊

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