Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma.

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作者： Chloe N,Thomas ^[1] ; Alexandra,Bernardo-Colón ^[2] ; Ella,Courtie ^[3] ; Gareth,Essex ^[1] ; Tonia S,Rex ^[4] ; Richard J,Blanch ^[1] ; Zubair,Ahmed ^[3]

作者单位： Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. ^[1] School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. ^[2] Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA. ^[3] Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. ^[4] Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, TN, USA. ^[5] Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. r.j.blanch@bham.ac.uk. ^[6] Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. r.j.blanch@bham.ac.uk. ^[7] Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham, UK. r.j.blanch@bham.ac.uk. ^[8] Centre for Trauma Sciences Research, University of Birmingham, Birmingham, B15 2TT, UK. r.j.blanch@bham.ac.uk. ^[9] Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. z.ahmed.1@bham.ac.uk. ^[10] Centre for Trauma Sciences Research, University of Birmingham, Birmingham, B15 2TT, UK. z.ahmed.1@bham.ac.uk. ^[11]