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Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.

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作者: Yin,Yao [1] ; Zhian,Chen [2] ; Hao,Zhang [3] ; Cailing,Chen [4] ; Ming,Zeng [4] ; Joseph,Yunis [2] ; Yunbo,Wei [5] ; Yanmin,Wan [6] ; Naiqi,Wang [7] ; Mingzhe,Zhou [8] ; Chao,Qiu [9] ; Qunxiong,Zeng [10] ; Hong Sheng,Ong [11] ; Hao,Wang [11] ; Fadzai Victor,Makota [11] ; Yang,Yang [7] ; Zhaohui,Yang [12] ; Nan,Wang [4] ; Jun,Deng [13] ; Chao,Shen [14] ; Yan,Xia [12] ; Lin,Yuan [12] ; Zhaoqin,Lian [4] ; Yike,Deng [4] ; Cuilian,Guo [4] ; Ao,Huang [4] ; Pengcheng,Zhou [11] ; Haibo,Shi [15] ; Weitian,Zhang [15] ; Hongliang,Yi [15] ; Dongmei,Li [16] ; Ming,Xia [17] ; Jing,Fu [18] ; Ning,Wu [19] ; Judy B,de Haan [20] ; Nan,Shen [10] ; Wenhong,Zhang [21] ; Zheng,Liu [22] ; Di,Yu [23]
作者单位: Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.;The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, Australia.;Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australia. [1] The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, Australia.;Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australia. [2] Laboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.;Hubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Minda Hospital of Hubei Minzu University, Enshi, China. [3] Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [4] Laboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China. [5] Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.;Department of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China. [6] The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, Australia. [7] State Key Laboratory of Translational Medicine and Innovative Drug Development, Simcere Diagnostics Co., Ltd., Nanjing, China. [8] Minhang Hospital and Huashan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China. [9] China-Australia Centre for Personalised Immunology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. [10] Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australia. [11] Hubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Minda Hospital of Hubei Minzu University, Enshi, China. [12] Hubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Minda Hospital of Hubei Minzu University, Enshi, China.;China-Australia Centre for Personalised Immunology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. [13] State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China. [14] Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. [15] Department of Otolaryngology, Qilu Children's Hospital of Shandong University, Jinan, China. [16] Department of Otolaryngology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Key Laboratory for Hearing Reconstruction of Shandong Province, Jinan, China. [17] Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, Australia. [18] Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [19] Baker Heart and Diabetes Institute, Monash University, Melbourne, Australia. [20] Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China. [21] Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. zhengliuent@hotmail.com. [22] The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, Australia. di.yu@uq.edu.au.;Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australia. di.yu@uq.edu.au.;Laboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China. di.yu@uq.edu.au.;Hubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Minda Hospital of Hubei Minzu University, Enshi, China. di.yu@uq.edu.au.;China-Australia Centre for Personalised Immunology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. di.yu@uq.edu.au. [23]
DOI 10.1038/s41590-021-00996-0
PMID 34413521
发布时间 2024-08-08
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