MBD2 acts as a repressor to maintain the homeostasis of the Th1 program in type 1 diabetes by regulating the STAT1-IFN-γ axis.
第一作者:
Tiantian,Yue
第一单位:
The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, China.
作者:
医学主题词
动物(Animals);DNA甲基化(DNA Methylation);DNA结合蛋白质类(DNA-Binding Proteins);糖尿病, 1型(Diabetes Mellitus, Type 1);内环境稳定(Homeostasis);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);STAT1转录因子(STAT1 Transcription Factor)
DOI
10.1038/s41418-021-00852-6
PMID
34420035
发布时间
2023-02-06
- 浏览1
Cell death and differentiation
218-229页
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