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High DNMT1 Is Associated With Worse Local Control in Early-Stage Laryngeal Squamous Cell Carcinoma.

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第一作者： Leonie,Bruine de Bruin

第一单位： Department of Otorhinolaryngology/Head and Neck Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.;Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

作者： Leonie,Bruine de Bruin ^[1] ; Martijn J A M,Clausen ^[2] ; Lorian,Slagter-Menkema ^[1] ; Gertruida H,de Bock ^[3] ; Johannes A,Langendijk ^[4] ; Bert,van der Vegt ^[5] ; Bernard F A M,van der Laan ^[6] ; Ed,Schuuring ^[5]

作者单位： Department of Otorhinolaryngology/Head and Neck Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.;Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[1] Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.;Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[2] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[3] Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[4] Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[5] Department of Otorhinolaryngology/Head and Neck Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[6]

关键词 DNA methylation Laryngeal squamous cell carcinoma local control prognostic marker radiotherapy