Brain erythropoietin fine-tunes a counterbalance between neurodifferentiation and microglia in the adult hippocampus.

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第一作者： Laura,Fernandez Garcia-Agudo

第一单位： Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

作者： Laura,Fernandez Garcia-Agudo ^[1] ; Agnes A,Steixner-Kumar ^[1] ; Yasmina,Curto ^[1] ; Nadine,Barnkothe ^[1] ; Imam,Hassouna ^[1] ; Sebastian,Jähne ^[2] ; Umer Javed,Butt ^[1] ; Katharina,Grewe ^[2] ; Martin S,Weber ^[3] ; Kim,Green ^[4] ; Silvio,Rizzoli ^[2] ; Juan,Nacher ^[5] ; Klaus-Armin,Nave ^[6] ; Hannelore,Ehrenreich ^[7]

作者单位： Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany. ^[1] Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, Göttingen, Germany. ^[2] Institute of Neuropathology and Department of Neurology, UMG, Göttingen, Germany. ^[3] Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA. ^[4] Neurobiology Unit, Program in Neurosciences and Interdisciplinary Research Structure for Biotechnology and Biomedicine (BIOTECMED), Universitat de València, Burjassot, Spain. ^[5] Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany. ^[6] Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany. Electronic address: ehrenreich@em.mpg.de. ^[7]

关键词 CSF1R IL-34 PLX5622 apoptosis hypoxia microglia activity neurodifferentiation neurogenesis proliferation recombinant human EPO