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首页> Genes> Prediction of Parkinson's Disease Risk Based on Genetic Profile and Established Risk Factors.

Prediction of Parkinson's Disease Risk Based on Genetic Profile and Established Risk Factors.

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作者： Paraskevi P,Chairta ^[1] ; Andreas,Hadjisavvas ^[2] ; Andrea N,Georgiou ^[3] ; Maria A,Loizidou ^[4] ; Kristia,Yiangou ^[2] ; Christiana A,Demetriou ^[3] ; Yiolanda P,Christou ^[2] ; Marios,Pantziaris ^[3] ; Kyriaki,Michailidou ^[5] ; Eleni,Zamba-Papanicolaou ^[1]

作者单位： Neurology Clinics, The Cyprus Institute of Neurology and Genetics, Nicosia 2371, Cyprus. ^[1] The Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, Nicosia 2371, Cyprus. ^[2] Department of Cancer Genetics, Therapeutics & Ultrastructural Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia 2371, Cyprus. ^[3] Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece. ^[4] Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia 2408, Cyprus. ^[5] Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, Nicosia 2371, Cyprus. ^[6]

关键词 Cypriot population PRS Parkinson’s disease SNPs case-control study environmental factors genetic variants polygenic risk score predictive model

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);人体质量指数(Body Mass Index);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);基因型(Genotype);人类(Humans);男(雄)性(Male);中年人(Middle Aged);多因子遗传(Multifactorial Inheritance);帕金森病(Parkinson Disease);多态性, 单核苷酸(Polymorphism, Single Nucleotide);危险因素(Risk Factors)

DOI 10.3390/genes12081278

PMID 34440451

发布时间 2022-02-07

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