Evaluation of Micro Satellite Instability and Mismatch Repair Status in Different Solid Tumors: A Multicenter Analysis in a Real World Setting.

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作者： Umberto,Malapelle ^[1] ; Paola,Parente ^[2] ; Francesco,Pepe ^[1] ; Caterina,De Luca ^[1] ; Pasquale,Pisapia ^[1] ; Roberta,Sgariglia ^[1] ; Mariantonia,Nacchio ^[1] ; Gianluca,Gragnano ^[1] ; Gianluca,Russo ^[1] ; Floriana,Conticelli ^[1] ; Claudio,Bellevicine ^[1] ; Elena,Vigliar ^[1] ; Antonino,Iaccarino ^[1] ; Claudia,Covelli ^[2] ; Mariangela,Balistreri ^[3] ; Celeste,Clemente ^[2] ; Giovanni,Perrone ^[2] ; Angela,Danza ^[2] ; Fabio,Scaramuzzi ^[2] ; Matteo,Fassan ^[3] ; Giancarlo,Troncone ^[4] ; Paolo,Graziano ^[1]

作者单位： Department of Public Health, University of Naples Federico II, 80131 Naples, Italy. ^[1] Unit of Pathology, Fondazione IRCCS Casa Sollievo Della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy. ^[2] Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35128 Padua, Italy. ^[3] Veneto Institute of Oncology, IOV-IRCCS, 35128 Padua, Italy. ^[4]

关键词 IHC MMR MSI fully automated RT-PCR immune checkpoint inhibitors (ICIs)immunotherapy microfluidic predictive molecular pathology

主题词 DNA错配修复(DNA Mismatch Repair);DNA修复酶类(DNA Repair Enzymes);消化系统肿瘤(Digestive System Neoplasms);子宫内膜肿瘤(Endometrial Neoplasms);女(雌)性(Female);生殖器肿瘤, 女(雌)性(Genital Neoplasms, Female);人类(Humans);免疫组织化学(Immunohistochemistry);意大利(Italy);男(雄)性(Male);微流体分析技术(Microfluidic Analytical Techniques);微卫星不稳定性(Microsatellite Instability);分子诊断技术(Molecular Diagnostic Techniques);卵巢肿瘤(Ovarian Neoplasms);胰腺肿瘤(Pancreatic Neoplasms);聚合酶链反应(Polymerase Chain Reaction);试验预期值(Predictive Value of Tests);前列腺肿瘤(Prostatic Neoplasms);结果可重复性(Reproducibility of Results);回顾性研究(Retrospective Studies);胃肿瘤(Stomach Neoplasms)

DOI 10.3390/cells10081878

PMID 34440647

发布时间 2021-11-16

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2021年10卷8期

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Evaluation of Micro Satellite Instability and Mismatch Repair Status in Different Solid Tumors: A Multicenter Analysis in a Real World Setting.

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Evaluation of Micro Satellite Instability and Mismatch Repair Status in Different Solid Tumors: A Multicenter Analysis in a Real World Setting.

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